General

Scientific Names: Stemona sessilifolia (Miq.) Franch. et Sav.

Common Names: Zhi Li Bai Bu, Yao Feng Yao, Yi Wo Hu.

BOTANICAL:

来 源： 百部科植物直立百部Stemona sessilifolia（Miq．）的块根。

植物特征： 多年生草本，高30～60cm。茎直立，不分枝。叶常3～4片轮生，卵形或椭圆形，长4～6cm，宽2～4cm，先端渐尖，主脉3～5；叶柄短或近无柄。花小，多生于茎下部鳞状叶腋间，有细长花梗，直立或向上斜生；花被片4，淡绿色；雄蕊4，药隔膨大并突出而有披针形附属物；子房卵形，无花柱。蒴果扁卵形。花期4～5月，果期7月。

生药材鉴定： 块根纺锤形，上端较细长，皱缩弯曲，长5～12cm，直径0.5～1cm。表面黄白色或淡黄棕色，有不规则深纵沟及细皱纹，断面平坦，淡黄棕色或黄白色，皮部较宽，中柱扁缩。质脆。气微，味甘、苦。

Pharmacology

化学成分: 含直立百部碱（sessilistemonine）、霍多林碱（hordorine）、对叶百部碱（tuberostemonine）和原百部碱（protostemonine）等。

Efficacy

Several novel bioactive components isolated from Chinese medicinal plants will be presented. These include novel maytansinoid tumor inhibitors, some new ent-kaurane and rosane diterpenoids from Mallotus anomalus Meer et Chun (Euphorbiaceae), as well as novel insecticide, stemona alkaloids from Stemona parviflora C. H. Wright (Stemonaceae). Both are native plants of Hainan island, China. 2D NMR techniques such as mono and hetero-COSY, NOESY, COLOC as well as 1H-NMR line broadening effect were utilized for structure elucidation. The separation techniques, structure elucidations and bioassay results will be reported. (source)

IN VITRO:

1. Rinner B, et al., Activity of novel plant extracts against medullary thyroid carcinoma cells. Anticancer Res. 2004 Mar-Apr; 24(2A):495-500.
2. Zhao W, et al., Bibenzyls from Stemona tuberosa. Phytochemistry. 1995 Feb; 38(3):711-3.
3. Xu RS, et al., Studies on bioactive components from Chinese medicinal plants. Mem Inst Oswaldo Cruz. 1991; 86 Suppl 2:55-9.
   
   

Safety