Experimental Study on Antitumor Effects of Dioscorea in Vitro

Liu Jiang-tao, Chen Xin-yi, Wang Yu-zhi

Objective : Study on antitumor effects of Dioscorea.

Methods : By MTT assay in vitro.

Results : The IC50 of dioscorea in DMSO and PBS for KB and KBv200 cells were (4.13 ± 0.40) mcg / mL and (4.20 ± 0.63) mcg/mL without cross-resistance.

Conclusion: Dioscorea has remarkable antitumor effect.

Key words: plant tumor cell; MTTassay; KB/KBv200 cell line; Dioscorea