General

Scientific Names: Ixeris denticulata (Houtt) Stebb

Common Names: Ku Mai Cai, Ku Cai, Pan Er Cao, Bai Jiang Cao.

BOTANICAL:

来 源： 为菊科植物苦荬菜Ixeris denticulata(Houtt.)Stebb.的全草。

植物特征： 苦荬菜为一或二年生草本，无毛，植株有乳汁，高30～80厘米；茎直立，常带紫红色，多分技。基生叶长圆形、披针形或卵状披针形，长5～9厘米，宽2～4厘米，边缘具波状齿或羽裂，开花时枯萎；茎生叶互生，阔椭圆状披针形或阔长圆形，无柄，基部耳状，略抱茎，边缘具大小不等的齿裂，稀为全缘。头状花序直径约1.3～1.5厘米，多聚集成伞房状，总苞圆筒形，无毛，外层总苞片小，内层总苞片远大于外层；花冠黄色，全为舌状花，长7～8毫米，截头，顶端具5齿；雄蕊5，花药连合；花柱细长，柱头2裂。瘦果纺锤形，熟时黑褐色，长约3毫米，冠毛白色。花果期9～11月。

生药材鉴定： 本品长30～70厘米。茎纤细，圆柱形，直径2～4毫米，外表黄绿色至绿紫色，质硬而脆，折断面髓部类白色。叶黄绿色至草黄色，多皱缩或破碎，完整者展平后呈宽卵状披针形或长圆形，边缘具不整齐锯齿。茎顶端着生有黄色头状花序。气微，味微苦。以身干、色绿、质嫩、无泥沙及杂质者为佳。

Pharmacology

化学成分: 含黃酮 苷 約 0.5% 。

Efficacy

An extract from the entire Ixeris denticulata f. pinnatipartita plant afforded the guaianolide sesquiterpene lactone glucoside, 8 beta,15-dihydroxy-1(10),3,11(13)-guaiatrien-12,6-olide-15-O- glucopyranoside, along with the known flavonoids luteolin-7-O-glucoside and luteolin-7-O-glucuronide-6'-methyl ester; their structures were determined by spectroscopic methods. Ixerin Y inhibited the growth of human breast cancer MCF7 and MDA468 cell lines. (source)

IN VITRO:

1. Ma JY, et al., A sesquiterpene lactone glucoside from Ixeris denticulata f. pinnatipartita. Phytochemistry. 1999 Jan; 50(1):113-5.
   
   
   
   
   

Safety