General

Scientific Names: Iris pallasii var. chinesnsis

Common Names: Ma Lan Zi, Ma Lian Zi.

BOTANICAL:

来 源： 为植物鸢尾科马蔺Iris pallasii Fisch.var.chinensis Fisch.的种子。

植物特征： 多年生草本。根状茎短而粗壮；根棕褐色，细长而坚韧。叶基生，成丛，坚韧，叶鞘枯死后常裂成细长纤维状的残留物，叶片条形，长达40cm，宽达6mm，灰绿色，先端渐尖，基部带紫色，全缘，两面具7～10条突起的平行脉。花葶从叶丛中抽出，高10～30cm，顶端有花1～3，苞片3，叶状，窄矩圆状披针形；花蓝紫色，花被6，外轮3，花被片较大，匙形，向外弯曲而下垂，中部有黄色条纹，内轮3花被片倒披针形，直立，花被下部联合成筒状；花柱3深裂，花瓣状，顶端2裂。蒴果长椭圆形，长4～6cm，具6条纵肋，先端具尖喙；种子近球形或不规则形，棕褐色，有棱角。

生药材鉴定： 本品呈不规则圆形，具条棱，长2.5～4.5mm,宽达3.5mm。棕褐色至棕黑 色，基部有黄棕色种脐，顶端有略突起的合点。质坚硬。切断面胚乳肥厚，灰白色，角质状。胚白色，细小，弯曲状。气微，味淡。

Pharmacology

化学成分: 种皮的醚溶部分含马蔺子甲素Pallason A (Irisquinone)、马蔺子乙素Pallason B (dihydroirisquinone)、马蔺子丙素Pallason C、β-谷甾醇、三萜类化合物及植物蜡。

Efficacy

The experience of traditional Chinese medicine affords a valuable approach in the search for new antineoplastic drugs as illustrated by indirubin from Dang Gui Lu Hui Wan, irisquinone from Iris lactea pallasii and Zhuling polysaccharide from Polyporus umbellata. The application of chemotaxonomic principles to related species of those plants used in folk medicine has also provided an approach which can be used successfully for the development of new drugs. The studies of Cephalotaxus hainanesis and Camptotheca accuminata provide two typical examples in this regard. One must be aware that the experience of traditional Chinese medicine cannot be used without elaborate efforts in many cases. For example, the ancient Chinese ideograph for spleen does not mean spleen in the modern sense, instead it refers to the entire gastrointestinal system. Similarly, the ancient ideograph for kidney does not mean kidney in the modern sense, and can mean the entire endocrine system. Therefore, for the reasonable utilization of traditional Chinese medicine, one must be familiar with its basic concepts and terminology. In addition, one must bear in mind that the term "tumor" in folk medicine is applied to a very wide range of pathological manifestations which sometimes have no relation to the various forms of neoplasia. It is important for drugs and treatments to be analyzed carefully in modern terms to eliminate the false and to utilize the true information. Only in such a way can the experience of traditional medicine be integrated into modern medicine and make its contribution in the advancement of health care in the world. (source)

具抗癌活性：在动物体内对移植性肿瘤小鼠宫颈癌症4、艾氏腹水癌、淋巴肉瘤、实体型和膜水型肝癌癌细胞均有抑制作用。

败毒抗癌，用于癌瘤积毒：

　　 肝癌 马蔺子、广郁金各6克，酢奖草9克，山豆根、糯稻根各12克，马鞭草、四季青各15克 水煎2次分服，每次送服鳖甲煎丸6克，日1剂。能抗癌止血，解毒消肿。继续服用能使症状与包块消失，病情明显好转。

　　 宫颈癌 马蔺子、凤眼草各6克，木贼草9克，红藤、铁扫帚、鱼腥草各15克，海螵蛸、土茯苓各24克，石南藤、伏牛花根、橼木根各30克 水煎服，日1剂。能使带下、出血停止，肿疡、疼痛缓解，一般情况良好。

　　 扁桃体癌 马蔺子60克，升麻30克 共捣细为散，每爱莫能助了9克，密水调服。能使肿痛消除，咽部不适缓解。

　　 阴茎癌 马蔺子蚤休各45克，制马钱子、山慈姑、制蜈蚣各30克，紫草、黄连各15克，熟大黄9克，莪术、三棱、山豆根、漏芦、党参、苋芪、银花、菊花、海藻各 60克 共研细末，用紫石英1000克煅红，置于2000克黄醋水中，冷后过滤，以此醋泛为菊灌丸，梧子大，每服10克，日2次，饮后1小时温开水送服，持续服 用。同时局部用：水银、白矾、青矾、牙硝各180克，食盐90克 用降丹法炼制成五虎丹白色结晶，用此结晶1.2克，蟾酥、红娘、斑蝥（去头足）各0.5克，洋金花1克，以米糊2克调成筒糊，用米饭赋形制成两头尖的棱状 钉，随干为五虎丹钉剂，每支长4厘花，重约0.72克，可插入突出皮肤癌癌肿中央。神癌肿大小，可1次插入2~3支，待第1次上药处的肿块组织坏死脱落 后，再上第2次，然后用外科膏药覆盖固定。直至完全脱落，本病理检查无癌细胞后接用红升丹，最后用生肌散收口。亦用于治疗皮肤癌、乳腺癌、女阴癌、唇癌等 体表癌。 (source)

IN VITRO:

1. Han R. Highlight on the studies of anticancer drugs derived from plants in China. Stem Cells. 1994 Jan; 12(1):53-63.
2. Han J. Traditional Chinese medicine and the search for new antineoplastic drugs. J Ethnopharmacol. 1988 Sep; 24(1):1-17. Review.
   
   
   
   
   

Safety