General

Scientific Names: Stemona japonica (Bl.) Miq.

Common Names:Man Sheng Bai Bu, Yao Feng Yao.

BOTANICAL:

来 源： 为百部科植物蔓生百部Stemona japonica（Bl．）Miq.的块根。

植物特征： 多年生缠绕草本。茎长达100cm。叶2～4（～5）片轮生，叶柄长1.5～3cm；叶片卵形至卵状披针形，长3～9cm，宽1.5～4cm，先端渐尖。基部圆形或宽楔形，边缘带微波状，叶脉5～9条。花单生或数朵排成聚伞花序，总花梗完全贴生于叶片中脉上；花被片4，开放后向外反卷；雄蕊花药顶端有一短钻状附属物。蒴果卵状，稍扁。种子深紫褐色。花期4～5月，果期7月。

生药材鉴定： 根与直立百部类同，两端稍狭细，表面淡灰白色，多不规则皱褶及横皱纹；味较苦。

Pharmacology

化学成分: 含百部碱（stemonine）、次百部碱（stemonidine）、异次百部碱(isoste-monidine）、原百部碱（protostemonine）、蔓生百部碱（stemonamine）、异蔓生百部碱（isostemonamine）等。

Efficacy

Several novel bioactive components isolated from Chinese medicinal plants will be presented. These include novel maytansinoid tumor inhibitors, some new ent-kaurane and rosane diterpenoids from Mallotus anomalus Meer et Chun (Euphorbiaceae), as well as novel insecticide, stemona alkaloids from Stemona parviflora C. H. Wright (Stemonaceae). Both are native plants of Hainan island, China. 2D NMR techniques such as mono and hetero-COSY, NOESY, COLOC as well as 1H-NMR line broadening effect were utilized for structure elucidation. The separation techniques, structure elucidations and bioassay results will be reported. (source)

体外对肿瘤细胞有抑制作用，体内有抑制肿瘤生长作用。有抗噬菌体作用。

IN VITRO:

1. Rinner B, et al., Activity of novel plant extracts against medullary thyroid carcinoma cells. Anticancer Res. 2004 Mar-Apr; 24(2A):495-500.
2. Zhao W, et al., Bibenzyls from Stemona tuberosa. Phytochemistry. 1995 Feb; 38(3):711-3.
3. Xu RS, et al., Studies on bioactive components from Chinese medicinal plants. Mem Inst Oswaldo Cruz. 1991; 86 Suppl 2:55-9.

Safety