General

Scientific Names: Salvia chinensis Benth.

Common Names: Zi Shen, Shi Jian Chuan, Shi Da Chuan, Yue Xia Hong.

BOTANICAL:

中药材基原: 为唇形科植物华鼠尾Salvia chinensis Benth. 的全草。

植物形态: 一年生草本，高20～70cm。茎方形，单一或分枝，表面紫棕色或绿色，被倒向柔毛。叶对生，全为单叶或茎下部为三出复叶，卵形或卵状椭圆形，长1.3～7cm，边缘有圆齿。轮伞花序6花，集成假总状或圆锥花序；花萼钟状，紫色；花冠蓝紫色或紫色，外被长柔毛；雄蕊2，花丝短，药隔长；子房4裂，花柱着生子房底。小坚果椭圆状卵形，褐色。花期7～8月，果期9～10月。

资源分布: 生于山坡、路旁、林缘及草丛中。主产江苏、浙江、安徽亦产。

Pharmacology

化学成分: 全草含甾醇、三萜类、氨基酸、原儿茶醛；根含水苏糖（stachyose）。

Efficacy

Aqueous extracts of 12 Chinese medicinal herbs, Anemarrhena asphodeloides, Artemisia argyi, Commiphora myrrha, Duchesnea indica, Gleditsia sinensis, Ligustrum lucidum, Rheum palmatum, Rubia cordifolia, Salvia chinensis, Scutellaria barbata, Uncaria rhychophylla and Vaccaria segetalis were evaluated for their antiproliferative activity on eight cancer cell lines as well as on normal human mammary epithelial cells. Five human and three murine cancer cell lines representing different tissues (breast, lung, pancreas and prostate) were used. All the crude aqueous extracts demonstrated growth inhibitory activity on some or all of the cancer cell lines, but only two showed activity against the normal mammary epithelial cells. Overall, the murine cell lines tended to be more sensitive to most of the extracts compared with the human cell lines. Among the human cell lines, cell type specificity was observed for two extracts. These results indicate the potential use of traditional Chinese medicinal herbs as antineoplastic agents and suggest that further studies evaluating their mechanism(s) of action and the isolation of active antitumor compounds are warranted. (source)

败毒抗癌，用于癌瘤积毒：

食管癌 石见穿、半枝莲、急性子各30克，红枣5枚 水煎服，日1剂。能使胸腹胀闷、吞咽困难等症状消失，癌肿缩小。

胃癌 石见穿30克，北沙参、丹参、全瓜萎、代赭石各15克，郁金、枳壳、法半夏各9克，旋复花（包煎）、佛手片各6克 水煎2次分服。能缓和胀痛，缩小肿块。

肝癌 石见穿、丹参、夏枯草各30克，七叶一枝花、党参、香附、马鞭草、虎杖各15克，鹅不食草9克，守宫5条 水煎服，日1剂。另用鲜蟾蜍皮外贴肝肿处。继续服用，能使疼痛减轻，食欲增加，肝肿大明显缩小。

宫颈癌 石见穿、六月雪、墓头回各30克，香附15克 均用鲜品，水煎2次分服，日1剂。能使肿瘤修复，症状消失。

肺癌 石见穿、紫草根各30克，蒲公英、徐长卿各15克，沙参、麦冬、生地、百部、地榆各12克，炒山栀、王不留行各9克，五味子3克 水煎，分2次送服班蝥片（含斑蝥素0.003克）各1片。继续3个月，胸片复查肿瘤逐渐缩小，2年后临床症状基本消失。

鼻腔癌 石见穿30克 水煎2小时，日3次分服，亦可用鲜品汁30克内服。能使癌灶及症状消失。

IN VITRO:

1. Shoemaker M, et al., In vitro anticancer activity of twelve Chinese medicinal herbs. Phytother Res. 2005 Jul; 19(7): 649-51.

Safety