Current 2010 2009 or Earlier
Effect of Sanguisorba officinalis L on breast cancer growth and angiogenesis.
Wang Z, Loo WT, Wang N, Chow LW, Wang D, Han F, Zheng X, Chen JP.
Expert Opin Ther Targets. 2012 Feb 9.
Triptolide inhibits colon cancer cell proliferation and induces cleavage and translocation of 14-3-3 epsilon.
Liu Y, Song F, Wu WK, He M, Zhao L, Sun X, Li H, Jiang Y, Yang Y, Peng K.
Cell Biochem Funct. 2012 Feb 7. doi: 10.1002/cbf.2793
Polysaccharide peptides from Coriolus versicolor competitively inhibit model cytochrome P450 enzyme probe substrates metabolism in human liver microsomes.
Yeung JH, Or PM.
Phytomedicine. 2012 Feb 2.
Dehydrocorydaline inhibits breast cancer cells proliferation by inducing apoptosis in mcf-7 cells.
Xu Z, Chen X, Fu S, Bao J, Dang Y, Huang M, Chen L, Wang Y.
Am J Chin Med. 2012;40(1):177-85.
Tanshinones from Chinese Medicinal Herb Danshen (Salvia miltiorrhiza Bunge) Suppress Prostate Cancer Growth and Androgen Receptor Signaling.
Zhang Y, Won SH, Jiang C, Lee HJ, Jeong SJ, Lee EO, Zhang J, Ye M, Kim SH, L J.
Pharm Res. 2012 Jan 27
Analysis of tanshinone IIA induced cellular apoptosis in leukemia cells by genome-wide expression profiling.
Liu C, Li J, Wang L, Wu F, Huang L, Xu Y, Ye J, Xiao B, Meng F, Chen S, Yang M.
BMC Complement Altern Med. 2012 Jan 16;12(1):5.
Down-Regulation of Survivin and Hypoxia-Inducible Factor-1 by -elemene Enhances the Radiosensitivity of Lung Adenocarcinoma Xenograft.
Li G, Xie B, Li X, Chen Y, Wang Q, Xu Y, Xu-Welliver M, Zou L.
Cancer Biother Radiopharm. 2012 Jan 16
Purified Vitexin Compound 1 Suppresses Tumor Growth and Induces Cell Apoptosis in a Mouse Model of Human Choriocarcinoma.
Tan Z, Zhang Y, Deng J, Zeng G, Zhang Y.
Int J Gynecol Cancer. 2012 Jan 6.
Anticancer Potential of Euphorbia helioscopia L Extracts Against Human Cancer Cells.
Wang ZY, Liu HP, Zhang YC, Guo LQ, Li ZX, Shi XF.
Anat Rec (Hoboken). 2012 Feb;295(2):223-33. doi: 10.1002/ar.21517
A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit. Tang WM, Chan E, Kwok CY, Lee YK, Wu JH, Wan CW, Chan RY, Yu PH, Chan SW.
Inflammopharmacology. 2011 Dec 22
Astragalus membranaceus lectin (AML) induces caspase-dependent apoptosis in human leukemia cells.
Huang LH, Yan QJ, Kopparapu NK, Jiang ZQ, Sun Y.
Cell Prolif. 2012 Feb;45(1):15-21. doi:10.1111/j.1365-2184.2011.00800.x.
Matrine inhibits proliferation and induces apoptosis of the androgen independent prostate cancer cell line PC-3.
Zhang P, Wang Z, Chong T, Ji Z.
Mol Med Report. 2012 Mar;5(3):783-7. doi: 10.3892/mmr.2011.701
Induction of actin disruption and downregulation of P-glycoprotein expression by solamargine in multidrug-resistant K562/A02 cells.
Li X, Zhao Y, Ji M, Liu SS, Cui M, Lou HX.
Chin Med J (Engl). 2011 Jul 5;124(13):2038-44
An improved high performance liquid chromatography-photodiode array detection-atmospheric pressure chemical ionization-mass spectrometry method for determination of chlorophylls and their derivatives in freeze-dried and hot-air-dried Rhinacanthus nasutus (L.) Kurz.
Kao TH, Chen CJ, Chen BH.
Talanta. 2011 Oct 30;86:349-55
Effects of a Chinese Herbal Medicine, Guan-Jen-Huang (Aeginetia indica Linn.), on Renal Cancer Cell Growth and Metastasis.
Liu YH, Li ML, Hsu MY, Pang YY, Chen IL, Chen CK, Tang SW, Lin HY, Lin JY.
Evid Based Complement Alternat Med. 2012;2012:935860
Dihydroartiminisin inhibits the growth and metastasis of epithelial ovarian cancer.
Wu B, Hu K, Li S, Zhu J, Gu L, Shen H, Hambly BD, Bao S, Di W.
Oncol Rep. 2012 Jan;27(1):101-8. doi: 10.3892/or.2011.1505.
Phenolic compounds from the whole plants of Gentiana rhodantha (Gentianaceae).
Xu M, Zhang M, Wang D, Yang CR, Zhang YJ.
Chem Biodivers. 2011 Oct;8(10):1891-900.
NF-B, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G /M cell cycle arrest.
Yin Y, Chen W, Tang C, Ding H, Jang J, Weng M, Cai Y, Zou G.
Food Chem Toxicol. 2011 Dec;49(12):3046-54
Anti-proliferative effects of Chinese herb Cornus officinalis in a cell culture model for estrogen receptor-positive clinical breast cancer.
Telang NT, Li G, Sepkovic DW, Bradlow HL, Wong GY.
Mol Med Report. 2012 Jan;5(1):22-8.
Tubeimoside-1 induces G2/M phase arrest and apoptosis in SKOV-3 cells through increase of intracellular Ca and caspase-dependent signaling pathways.
Chen WJ, Yu C, Yang Z, He JL, Yin J, Liu HZ, Liu HT, Wang YX.
Int J Oncol. 2012 Feb;40(2):535-43.
Celastrol-induced apoptosis in human HaCaT keratinocytes involves the inhibition of NF-B activity.
Zhou LL, Lin ZX, Fung KP, Cheng CH, Che CT, Zhao M, Wu SH, Zuo Z.
Eur J Pharmacol. 2011 Nov 30;670(2-3):399-408.
Salvianolic acid B modulates the expression of drug-metabolizing enzymes in HepG2 cells.
Wang QL, Wu Q, Tao YY, Liu CH, El-Nezami H.
Hepatobiliary Pancreat Dis Int. 2011 Oct;10(5):502-8.
Triptolide (TPL) inhibits global transcription by inducing proteasome-dependent degradation of RNA polymerase II (Pol II).
Wang Y, Lu JJ, He L, Yu Q.
PLoS One. 2011;6(9):e23993
Antrodia camphorata induces apoptosis and enhances the cytotoxic effect of paclitaxel in human ovarian cancer cells.
Liu FS, Yang PY, Hu DN, Huang YW, Chen MJ.
Int J Gynecol Cancer. 2011 Oct;21(7):1172-9.
Ginsenoside Re: Pharmacological Effects on Cardiovascular System.
Peng L, Sun S, Xie LH, Wicks SM, Xie JT.
Cardiovasc Ther. 2011 Apr 1.
Effects of a Chinese medical herbs complex on cellular immunity and toxicity-related conditions of breast cancer patients.
Zhuang SR, Chiu HF, Chen SL, Tsai JH, Lee MY, Lee HS, Shen YC, Yan YY, Shane GT, Wang CK.
Br J Nutr. 2012 Mar;107(5):712-8.
Protective effects of diosmetin extracted from Galium verum L. on the thymus of U14-bearing mice.
Zhao R, Chen Z, Jia G, Li J, Cai Y, Shao X.
Can J Physiol Pharmacol. 2011 Sep;89(9):665-73.
Antiproliferation of melanoma cells by polysaccharide isolated from Zizyphus jujuba.
Hung CF, Hsu BY, Chang SC, Chen BH.
Nutrition. 2012 Jan;28(1):98-105.
Triptolide, histone acetyltransferase inhibitor, suppresses growth and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK pathway.
Park B, Sung B, Yadav VR, Chaturvedi MM, Aggarwal BB.
Biochem Pharmacol. 2011 Nov 1;82(9):1134-44.
Acetylbritannilactone suppresses growth via upregulation of krppel-like transcription factor 4 expression in HT-29 colorectal cancer cells.
Fang XM, Liu B, Liu YB, Wang JJ, Wen JK, Li BH, Han M.
Oncol Rep. 2011 Nov;26(5):1181-7.
Dioscorea phytocompounds enhance murine splenocyte proliferation ex vivo and improve regeneration of bone marrow cells in vivo.
Su PF, Li CJ, Hsu CC, Benson S, Wang SY, Aravindaram K, Chan SI, Wu SH, Yang FL, Huang WC, Shyur LF, Yang NS.
Evid Based Complement Alternat Med. 2011;2011:731308
Celecoxib and acetylbritannilactone interact synergistically to suppress breast cancercell growth via COX-2-dependent and -independent mechanisms.
Liu B, Wen JK, Li BH, Fang XM, Wang JJ, Zhang YP, Shi CJ, Zhang DQ, Han M.
Cell Death Dis. 2011 Jul 28;2:e185.
Anti-tumor potential of ethanol extract of Curcuma phaeocaulis Valeton against breastcancer cells.
Chen X, Pei L, Zhong Z, Guo J, Zhang Q, Wang Y.
Phytomedicine. 2011 Nov 15;18(14):1238-43
Coprescription of Chinese Herbal Medicine and Western Medications among ProstateCancer Patients: A Population-Based Study in Taiwan.
Lin YH, Chen KK, Chiu JH.
Evid Based Complement Alternat Med. 2012;2012:147015
Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis incancer cells by transcriptional suppression of Mcl-1.
Polier G, Ding J, Konkimalla BV, Eick D, Ribeiro N, K hler R, Giaisi M, Efferth T, Desaubry L, Krammer PH, Li-Weber M.
Cell Death Dis. 2011 Jul 21;2:e182
Inhibitive effect of triptolide on invasiveness of human fibrosarcoma cells by downregulating matrix metalloproteinase-9 expression.
Yang S, Gu C, Zhang G, Kang J, Wen H, Lu Q, Huang J.
Asian Pac J Trop Med. 2011 Jun;4(6):482-5
Polysaccharide peptides from Coriolus versicolor competitively inhibit tolbutamide 4-hydroxylation in specific human CYP2C9 isoform and pooled human liver microsomes.
Yeung JH, Or PM.
Phytomedicine. 2011 Oct 15;18(13):1170-5.
Deoxyelephantopin from Elephantopus scaber L. induces cell-cycle arrest and apoptosis in the human nasopharyngeal cancer CNE cells.
Su M, Chung HY, Li Y.
Biochem Biophys Res Commun. 2011 Jul 29;411(2):342-7.
A ten-year audit of traditional Chinese medicine and other natural product research published in the Chinese Medical Journal (2000-2009).
Collins RA.
Chin Med J (Engl). 2011 May;124(9):1401-8.
Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c.
Ling Q, Xu X, Wei X, Wang W, Zhou B, Wang B, Zheng S.
J Exp Clin Cancer Res. 2011 Jun 29;30:66.
The main anticancer bullets of the Chinese medicinal herb, thunder god vine.
Liu Z, Ma L, Zhou GB.
Molecules. 2011 Jun 23;16(6):5283-97. Review.
Polyphyllin D, a steroidal saponin from Paris polyphylla, inhibits endothelial cell functions in vitro and angiogenesis in zebrafish embryos in vivo.
Chan JY, Koon JC, Liu X, Detmar M, Yu B, Kong SK, Fung KP.
J Ethnopharmacol. 2011 Sep 1;137(1):64-9. Epub 2011 May 31.
Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer.
Ma L, Wen ZS, Liu Z, Hu Z, Ma J, Chen XQ, Liu YQ, Pu JX, Xiao WL, Sun HD, Zhou GB.
PLoS One. 2011;6(5):e20159. Epub 2011 May 31.
Use of Chinese medicine by women with breast cancer: a nationwide cross-sectional study in Taiwan.
Lin YH, Chiu JH.
Complement Ther Med. 2011 Jun;19(3):137-43. Epub 2011 May 2.
Cytotoxicity of Triptolide and Triptolide loaded polymeric micelles in vitro.
Zheng S, L w K, Wagner S, Yang X, von Briesen H, Zou S.
Toxicol In Vitro. 2011 Dec;25(8):1557-67. Epub 2011 May 27
-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis.
Liu J, Zhang Y, Qu J, Xu L, Hou K, Zhang J, Qu X, Liu Y.
BMC Cancer. 2011 May 20;11:183.
Trichosanthin enhances anti-tumor immune response in a murine Lewis lung cancermodel by boosting the interaction between TSLC1 and CRTAM.
Cai Y, Xiong S, Zheng Y, Luo F, Jiang P, Chu Y.
Cell Mol Immunol. 2011 Jul;8(4):359-67. doi: 10.1038/cmi.2011.12.
Interaction of a traditional Chinese Medicine (PHY906) and CPT-11 on the inflammatory process in the tumor microenvironment.
Wang E, Bussom S, Chen J, Quinn C, Bedognetti D, Lam W, Guan F, Jiang Z, Mark Y, Zhao Y, Stroncek DF, White J, Marincola FM, Cheng YC.
BMC Med Genomics. 2011 May 11;4:38.
Fingerprint quality detection of Solanum nigrum using high-performance liquid chromatography-evaporative light scattering detection.
Wang L, Gao G, Bai Y, Luo W, Lin C, Jia Q.
Pharm Biol. 2011 Jun;49(6):595-601
Does triptolide induce lysosomal-mediated apoptosis in human breast cancer cells?
Messina ME Jr, Halaby R.
Med Hypotheses. 2011 Jul;77(1):91-3. Epub 2011 Apr 12.
Honokiol produces anti-neoplastic effects on melanoma cells in vitro.
Mannal PW, Schneider J, Tangada A, McDonald D, McFadden DW.
J Surg Oncol. 2011 Sep 1;104(3):260-4.
Typhonium blumei extract inhibits proliferation of human lung adenocarcinoma A549 cells via induction of cell cycle arrest and apoptosis.
Hsu HF, Huang KH, Lu KJ, Chiou SJ, Yen JH, Chang CC, Houng JY.
J Ethnopharmacol. 2011 May 17;135(2):492-500
Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria- and Fas/FasL-mediated pathways.
Mou H, Zheng Y, Zhao P, Bao H, Fang W, Xu N.
Toxicol In Vitro. 2011 Aug;25(5):1027-32
The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lungcancer cells.
Gao J, Morgan WA, Sanchez-Medina A, Corcoran O.
Toxicol Appl Pharmacol. 2011 Aug 1;254(3):221-8
Chan-Yu-Bao-Yuan-Tang induces apoptosis in NSCLC and SCLC cell lines via a mitochondria-mediated pathway.
Zhang Y, Zeng F, Liu X, Li Y, Zhou J, Huang Y, Wang Y, Zhou S, Zhu W, Shu E, Zhou G, Chen G.
Xenobiotica. 2011 Jul;41(7):593-602.
Downregulation of AP-1 gene expression is an initial event in the oridonin-mediated inhibition of colorectal cancer: studies in vitro and in vivo.
Jin H, Tan X, Liu X, Ding Y.
J Gastroenterol Hepatol. 2011 Apr;26(4):706-15.
Lu L, Qin A, Huang H, Zhou P, Zhang C, Liu N, Li S, Wen G, Zhang C, Dong W, Wang X, Dou QP, Liu J.
Eur J Pharmacol. 2011 May 11;658(2-3):242-7.
Aqueous extract of Curcuma aromatica induces apoptosis and G2/M arrest in human colon carcinoma LS-174-T cells independent of p53.
Hu B, Shen KP, An HM, Wu Y, Du Q.
Cancer Biother Radiopharm. 2011 Feb;26(1):97-104
Interruption of the MEK/ERK signaling cascade promotes dihydroartemisinin-induced apoptosis in vitro and in vivo.
Gao N, Budhraja A, Cheng S, Liu EH, Huang C, Chen J, Yang Z, Chen D, Zhang Z, Shi X.
Apoptosis. 2011 May;16(5):511-23.
Chinese red yeast rice inhibition of prostate tumor growth in SCID mice.
Hong MY, Henning S, Moro A, Seeram NP, Zhang Y, Heber D.
Cancer Prev Res (Phila). 2011 Apr;4(4):608-15.
Icariin and its derivative, ICT, exert anti-inflammatory, anti-tumor effects, and modulate myeloid derived suppressive cells (MDSCs) functions.
Zhou J, Wu J, Chen X, Fortenbery N, Eksioglu E, Kodumudi KN, Pk EB, Dong J, Djeu JY, Wei S.
Int Immunopharmacol. 2011 Jul;11(7):890-8.
Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectalcancer cells through activation of p53.
Li B, Zhao J, Wang CZ, Searle J, He TC, Yuan CS, Du W.
Cancer Lett. 2011 Feb 28;301(2):185-92.
Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice.
Gong Y, Li Y, Lu Y, Li L, Abdolmaleky H, Blackburn GL, Zhou JR.
Int J Cancer. 2011 Sep 1;129(5):1042-52.
Ultrasound-induced cell death of nasopharyngeal carcinoma cells in the presence of curcumin.
Wang X, Xia X, Xu C, Xu J, Wang P, Xiang J, Bai D, Leung AW.
Integr Cancer Ther. 2011 Mar;10(1):70-6.
Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors.
Johnson SM, Wang X, Evers BM.
J Surg Res. 2011 Jun 15;168(2):197-205
Beta-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis
Typhonium blumei extract inhibits proliferation of human lung adenocarcinoma A549 cells via induction of cell cycle arrest and apoptosis
Trichosanthin enhances anti-tumor immune response in a murine Lewis lung cancer model by boosting the interaction between TSLC1 and CRTAM
Glaucocalyxin A induces apoptosis in human leukemia HL-60 cells through mitochondria-mediated death pathway
Biologic activity of triptolide in t(8;21) acute myeloid leukemia cells
Spatholobus suberectus inhibits cancer cell growth by inducing apoptosis and arresting cell cycle at G2/M checkpoint
Corydalis yanhusuo W.T. Wang Extract Inhibits MCF-7 Cell Proliferation by Inducing Cell Cycle G2/M Arrest
* New anti-malaria, anti-cancer research by Dr Chang and his team
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